Globally, unrelated protein sequences appear random
نویسندگان
چکیده
منابع مشابه
Globally, unrelated protein sequences appear random
MOTIVATION To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared the frequencies of four- and five-amino acid word clumps (independent words) in proteins to the frequencies predicted by four random sequence models. RESULTS While the human proteome has many overrepresented word clumps...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2009
ISSN: 1460-2059,1367-4803
DOI: 10.1093/bioinformatics/btp660